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Daniel Dombeck

Professor, Wender-Lewis Teaching and Research Professor

PhD, Cornell University


Regions(s): Brain and Behavior; Systems Neuroscience

Research interest(s): Optical dissection of the neuronal circuits underlying mammalian navigation

Research Summary

Optical dissection of the neuronal circuits underlying mammalian navigation

The neuronal activity underlying mammalian spatial navigation represents one of the most striking examples of behavioral correlation in the brain. We are interested in the cellular and circuit mechanisms responsible for the neuronal activity that allows mammals to navigate and find their way to specific destinations. To accomplish this, we develop and apply novel optical and genetic techniques to perform cellular and subcellular resolution imaging and manipulation of neuronal population activity in mice navigating in virtual reality environments. By understanding the navigation circuitry, we hope to extract general principles about neuronal population dynamics in behaving mammals.

Selected Publications

Selected Honors/Awards

  • 2015  McKnight Scholar Award,  McKnight Foundation​
  • 2011  Whitehall Research Grant Award, Whitehall Foundation
  • 2011  Klingenstein Fellowship in the Neurosciences, Esther & Joseph Klingenstein Foundation
  • 2010  Chicago Biomedical Consortium (CBC) Junior Investigator Award
  • 2010  Searle Leadership Fund Award, Northwestern University
  • 2007  Research Award for Innovation in Neuroscience (RAIN) - Presidential Award Ceremony, Society for Neuroscience Annual Meeting
  • 2007-09  Patterson Trust Postdoctoral Fellowship Program in Brain Circuitry